Advanced therapies over the past 40 years have resulted in continuous improvement in survival rates for adults with life-threatening illnesses. This growth in survivorship has led to the identification and understanding of the unique health and psychological needs of survivors of blood and marrow transplantation. The University of Minnesota is a leader in the study and treatment of these long-term after effects of disease.  

Survivors of cancer and stem cell transplantation may face problems that are related to their original disease process, prior treatment, or both. These late-effects may include cardiovascular disease and fertility issues, psychological problems, and the development of second cancers. They may develop soon after therapy or as much as 20-30 years later. Some effects may be identified earlier, while others may present later and become chronic health issues. 

Recognizing the need for continued surveillance and screening of the growing survivor population, the Blood and Marrow Transplant program has developed an extensive long-term follow up program to provide risk-based health care and surveillance to transplant survivors. The Long-Term Follow-up Clinic is staffed by physicians, nurses, neuropsychologists, and social workers, who specialize in the needs of survivors and can provide a multidisciplinary clinical assessment. Evaluations include: a comprehensive treatment review and summary, physical examination, referrals to sub-specialty care as needed, neuropsychological screening, social services, and educational materials concerning the long term risks of treatment. Our team will happily communicate with you and your primary physician following your evaluation to ensure that you continue to receive appropriate care years following transplant. 

Our staff continues to study and learn about the long-term effects of hematopoeitic stem cell transplantation and is actively involved in many local and national research projects. Interested survivors are offered the opportunity to participate in these studies. Our clinic welcomes patients from any transplant center.

Common Late Effects

• Cardiopulmonary (heart dysfunction, decreased lung volume)
• Endocrine (growth and fertility)
• Musculoskeletal (stunted bone growth, joint problems)
• Second malignancies
• Neurocognitive (learning disabilities, visual motor skills, memory loss)
• Psychological (depression, post-traumatic stress)
• Dental (caries, gum disease)